12月27號(hào)(周六)下午、12月28號(hào)(周日)上午，上海復(fù)旦大學(xué)附屬中山醫(yī)院口腔頜面外科專家王洋主任，來(lái)徐礦總醫(yī)院進(jìn)行病區(qū)查房和手術(shù)

　　王洋主任曾在上海第九人民醫(yī)院從事口腔頜面外科10余年。臨床主要從事口腔頜面部良惡性腫瘤的診斷及外科治療，尤其擅長(zhǎng)晚期頭頸癌綜合治療，頜骨病變的切除及數(shù)字化技術(shù)輔助的精準(zhǔn)重建。

　　詳情咨詢：

　　蔣海濤醫(yī)生 19549103633

王洋

　　上海復(fù)旦大學(xué)附屬中山醫(yī)院口腔頜面外科副主任醫(yī)師

　　學(xué)術(shù)任職：

　　中國(guó)抗癌協(xié)會(huì)頭頸腫瘤整合康復(fù)專委會(huì)委員

　　中華口腔醫(yī)學(xué)會(huì)口腔頜面頭頸腫瘤專業(yè)委員會(huì)青年委員

　　中國(guó)初級(jí)保健基金會(huì)頭頸腫瘤專委會(huì)委員

　　上?？谇会t(yī)學(xué)會(huì)口腔頜面-頭頸腫瘤醫(yī)學(xué)專委會(huì)委員

　　主持課題：

　　國(guó)自然面上1項(xiàng)：

　　EREG介導(dǎo)腫瘤相關(guān)中性粒細(xì)胞炎癥級(jí)聯(lián)反應(yīng)重塑上皮源性腫瘤免疫抑制微環(huán)境的機(jī)制及應(yīng)用研究 49萬(wàn) 2025.01-2028.12

　　上海市自然基金2項(xiàng)：

　　外泌體Epiregulin調(diào)控PD-L1促進(jìn)口腔鱗癌免疫逃逸的作用及分子機(jī)制研究 20萬(wàn) 2021.7-2024.6 已結(jié)題

　　PLAG1-IGF2軸介導(dǎo)的細(xì)胞自噬作用對(duì)促進(jìn)多形性腺瘤惡性轉(zhuǎn)化的機(jī)制研究 20萬(wàn) 2017.5-2020.4 已結(jié)題

　　發(fā)表論文：

　　Longwei Hu, Yun Zhu, Yibo Guo, Chenping Zhang, Yang Wang#, Zhen Zhang#, Bredigite bioceramic-based barrier membrane promotes guided bone regeneration by orchestrating an immuno-modulatory and osteogenic microenvironment. Chemical Engineering Journal, Volume 485, 2024, 149686.

　　Wang Y*, Qu X, Jiang J, Sun J, Zhang C, He Y. Aesthetical and Accuracy Outcomes of Reconstruction of Maxillary Defect by 3D Virtual Surgical Planning. Front Oncol. 2021 Oct 19;11:718946.

　　Hu L, Wang Y*, Pan H, Kadir K, Wen J, Li S, Zhang C. Apoptosis repressor with caspase recruitment domain (ARC) promotes bone regeneration of bone marrow-derived mesenchymal stem cells by activating Fgf-2/PI3K/Akt signaling. Stem Cell Res Ther. 2021 Mar 16;12(1):185..

　　Liu S, Wang Y*, Han Y, Xia W, Zhang L, Xu S, Ju H, Zhang X, Ren G, Liu L, Ye W, Zhang Z, Hu J. EREG-driven oncogenesis of Head and Neck Squamous Cell Carcinoma exhibits higher sensitivity to Erlotinib therapy. Theranostics. 2020 Aug 25;10(23):10589-10605.

　　Wang Y*, Han Y, Xu S, Zhang L, Zhang X, Deng J, Ye W, Liu S. Targeting EGFR Enriches Stem Cell-Like Properties in Salivary Adenoid Cystic Carcinoma by Activating the Notch1 Pathway. Cancer Manag Res. 2020 Jul 31;12:6655-6663.

　　Qu X, Wang Z, Wu K, Wang Y#, Shan L. Zoledronate inhibits the differentiation potential of adipose-derived stem cells into osteoblasts in repairing jaw necrosis. Mol Cell Probes. 2020 Jun;51:101525.

　　Liu W, Wang Y*, Du G, Zhou Z, Yang X, Shi L. Potential association between oral mucosal nevus and melanoma: A preliminary clinicopathologic study. Oral Dis. 2020 Sep;26(6):1240-1245.

　　Wang Y*, Hu J, Wang Y, Ye W, Zhang X, Ju H, Xu D, Liu L, Ye D, Zhang L, Zhu D, Deng J, Zhang Z, Liu S. EGFR activation induced Snail-dependent EMT and myc-dependent PD-L1 in human salivary adenoid cystic carcinoma cells. Cell Cycle. 2018;17(12):1457-1470.

　　王洋*,徐橋石,王進(jìn)兵,等.股前外側(cè)皮瓣在修復(fù)口腔頜面腫瘤切除后復(fù)合眶內(nèi)容物缺失的上頜骨缺損中的應(yīng)用.中華整形外科雜志, 2021, 37(11):7.

　　曲行舟, 王震, Ong Hui Shan, 王明一, 王洋#. (2021). 導(dǎo)航輔助穿顴種植體植入修復(fù)雙側(cè)上頜骨缺損的臨床應(yīng)用. 中華整形外科雜志, 2021,, 37(5), 6.